Fenghua Meng Selected Research

Prodrugs

1/2022	CD44-targeting hydrophobic phosphorylated gemcitabine prodrug nanotherapeutics augment lung cancer therapy.
10/2017	Glutathione-Sensitive Hyaluronic Acid-Mercaptopurine Prodrug Linked via Carbonyl Vinyl Sulfide: A Robust and CD44-Targeted Nanomedicine for Leukemia.
10/2017	A Smart Nano-Prodrug Platform with Reactive Drug Loading, Superb Stability, and Fast Responsive Drug Release for Targeted Cancer Therapy.
7/2017	cRGD-installed docetaxel-loaded mertansine prodrug micelles: redox-triggered ratiometric dual drug release and targeted synergistic treatment of B16F10 melanoma.
1/2017	αvβ3 integrin-targeted micellar mertansine prodrug effectively inhibits triple-negative breast cancer in vivo.
11/2016	Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy.
4/2016	Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo.
8/2013	Acetal-linked paclitaxel prodrug micellar nanoparticles as a versatile and potent platform for cancer therapy.
10/2011	Acid-activatable prodrug nanogels for efficient intracellular doxorubicin release.
5/2011	Endosomal pH-activatable poly(ethylene oxide)-graft-doxorubicin prodrugs: synthesis, drug release, and biodistribution in tumor-bearing mice.

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Fenghua Meng Research Topics

Disease

102	Neoplasms (Cancer) 03/2024 - 01/2009
14	Breast Neoplasms (Breast Cancer) 12/2021 - 05/2011
13	Lung Neoplasms (Lung Cancer) 01/2022 - 06/2015
12	Hepatocellular Carcinoma (Hepatoma) 10/2020 - 08/2011
8	Melanoma (Melanoma, Malignant) 10/2022 - 01/2017
7	Glioma (Gliomas) 01/2022 - 12/2014
7	Glioblastoma (Glioblastoma Multiforme) 11/2021 - 12/2014
5	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2024 - 10/2017
5	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 01/2018
4	Triple Negative Breast Neoplasms 07/2023 - 01/2017
4	Neoplasm Metastasis (Metastasis) 12/2022 - 01/2022
4	Multiple Myeloma 10/2021 - 11/2017
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2018
3	Liver Neoplasms (Liver Cancer) 10/2020 - 03/2015
2	Prostatic Neoplasms (Prostate Cancer) 10/2023 - 12/2015
2	Inflammation (Inflammations) 03/2023 - 02/2022
2	Rheumatoid Arthritis 03/2023 - 02/2022
2	Hematologic Neoplasms (Hematological Malignancy) 03/2023 - 11/2017
2	Bites and Stings (Sting) 10/2022 - 01/2022
2	Body Weight (Weight, Body) 07/2017 - 01/2017
1	Reperfusion Injury 06/2023
1	Wounds and Injuries (Trauma) 06/2023
1	Myocardial Ischemia (Ischemic Heart Diseases) 06/2023

Drug/Important Bio-Agent (IBA)

30	MicellesIBA 01/2022 - 10/2009
28	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2022 - 01/2009
24	Peptides (Polypeptides)IBA 01/2023 - 07/2013
16	Proteins (Proteins, Gene)FDA Link 01/2023 - 08/2013
15	Hyaluronic Acid (Hyaluronan)IBA 10/2021 - 06/2014
13	Ethylene Glycol (Monoethylene Glycol)IBA 11/2019 - 08/2011
10	IntegrinsIBA 10/2023 - 12/2014
10	Small Interfering RNA (siRNA)IBA 06/2023 - 03/2010
10	LigandsIBA 01/2022 - 10/2013
10	ProdrugsIBA 01/2022 - 05/2011
8	Docetaxel (Taxotere)FDA Link 10/2023 - 07/2017
8	DisulfidesIBA 10/2023 - 12/2017
8	Paclitaxel (Taxol)FDA LinkGeneric 07/2023 - 03/2010
7	Transferrin (beta 2 Transferrin)IBA 01/2024 - 06/2014
7	cyclic arginine-glycine-aspartic acid peptideIBA 01/2023 - 06/2014
7	NanogelsIBA 10/2018 - 05/2011
7	caprolactoneIBA 01/2017 - 08/2011
7	Galactose (Galactopyranose)FDA LinkGeneric 09/2015 - 08/2011
5	Granzymes (Granzyme)IBA 01/2022 - 06/2015
5	Liposomes (Liposome)IBA 01/2018 - 10/2012
5	liposomal doxorubicin (Doxil)FDA Link 01/2018 - 10/2016
5	polyethylene glycol bis(succinimidyl succinate)IBA 01/2017 - 08/2013
4	CytokinesIBA 03/2023 - 01/2022
4	Methotrexate (Mexate)FDA LinkGeneric 03/2023 - 09/2015
4	Messenger RNA (mRNA)IBA 01/2023 - 12/2018
4	Folic Acid (Vitamin M)FDA LinkGeneric 01/2022 - 06/2014
4	AcidsIBA 01/2018 - 08/2013
3	NanovaccinesIBA 03/2024 - 10/2021
3	VaccinesIBA 03/2024 - 10/2021
3	AntigensIBA 01/2023 - 10/2021
3	BI 6727IBA 09/2022 - 01/2021
3	Apolipoproteins E (ApoE)IBA 01/2022 - 11/2018
3	ApolipoproteinsIBA 01/2022 - 11/2018
3	PolymersIBA 11/2021 - 05/2011
3	Cytochromes c (Cytochrome c)IBA 10/2020 - 08/2016
3	GE11 peptideIBA 01/2020 - 12/2017
3	ErbB Receptors (EGF Receptor)IBA 01/2018 - 07/2017
3	Thioctic Acid (Lipoic Acid)IBA 11/2017 - 05/2015
3	Glutathione (Reduced Glutathione)IBA 10/2017 - 11/2016
3	Maytansine (Maitansine)IBA 07/2017 - 11/2016
3	Glutamic Acid (Glutamate)FDA Link 11/2016 - 09/2015
2	Gemcitabine FDA Link 07/2023 - 01/2022
2	Therapeutic UsesIBA 01/2023 - 01/2022
2	MicroRNAs (MicroRNA)IBA 01/2023 - 10/2021
2	Immunologic Adjuvants (Immunologic Adjuvant)IBA 01/2023 - 01/2022
2	Pemetrexed (MTA)FDA Link 10/2022 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 02/2022 - 10/2021
2	acetyl- lysyl- prolyl- seryl- seryl- prolyl- prolyl- glutamyl- glutamic acid amideIBA 01/2022 - 10/2021
2	CPG-oligonucleotideIBA 01/2022 - 01/2022
2	Sorafenib (BAY 43-9006)FDA Link 11/2021 - 10/2020
2	Nucleic AcidsIBA 10/2021 - 05/2011
2	tributyl phosphate (TBP)IBA 10/2021 - 10/2020
2	AntibodiesIBA 10/2021 - 06/2014
2	DNA (Deoxyribonucleic Acid)IBA 10/2021 - 04/2015
2	Photosensitizing Agents (Photosensitizers)IBA 01/2021 - 05/2011
2	LDL Receptors (LDL Receptor)IBA 10/2020 - 11/2018
2	Transferrin Receptors (Transferrin Receptor)IBA 10/2020 - 01/2019
2	SaporinsIBA 01/2020 - 07/2018
2	IodineIBA 11/2019 - 01/2019
2	Iohexol (Omnipaque)FDA Link 01/2019 - 03/2017
2	Angiopep-2IBA 12/2018 - 01/2018
2	trimethylene carbonateIBA 05/2018 - 12/2016
2	Cell-Penetrating PeptidesIBA 01/2018 - 01/2018
2	Polysaccharides (Glycans)IBA 10/2017 - 06/2014
2	Matrix Metalloproteinases (MMPs)IBA 07/2017 - 01/2017
2	cyanine dye 5IBA 01/2017 - 11/2016
2	sigma Receptors (sigma Receptor)IBA 10/2016 - 06/2015
2	carbopol 940 (sodium polyacrylate)IBA 05/2014 - 08/2013

Therapy/Procedure

50	Therapeutics 10/2023 - 10/2009
39	Drug Therapy (Chemotherapy) 10/2022 - 08/2011
8	Immunotherapy 03/2024 - 10/2021
2	Adjuvant Chemotherapy 10/2022 - 09/2022
2	Radiotherapy 12/2021 - 11/2019
2	Molecular Targeted Therapy 11/2021 - 01/2021
2	RNAi Therapeutics 10/2021 - 12/2018
2	Precision Medicine 01/2019 - 12/2016
2	Intravenous Injections 01/2019 - 12/2016